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How
to treat scarring and skin damages resulted from acne is of great concern to patients
with moderate to severe acne. Failed or inadequate
treatment of acne is a major cause in development of scarring.
The same distress acne patients experience may follow with its disfiguring sequels. The incidence of these sequels is not known. It is frequently stated
that acne scarring results from severe inflammatory nodulocystic acne
lesions occurring deep in the dermis. Although it may exist with
only minor more superficial acne. It is very likely that some patients are further prone
to scars based the factors that define their skins. Of paramount importance that acne
should be treated early and adequately. See also the review of american academy of dermatology on skin scarring resulted from acne. Following factors may be
stated as involved in etiology and introduced as causes of acne scars.
- A scar can be natural consequence of inflammatory acne or result of self manipulation.
- An skin injury that extends into the dermis layer, it is always associated with development of a permanent lesion.
- Nodular
forms of active acne such as cystic and nodular acne are more
likely to form face scarring and an acne spots.
- Infection
is another involved factor in acne that comes into play and results
in severe acne scarring.
- Location of the comedones/ acne breakouts also becomes an important factor. Areas of the face with better circulation heal exceedingly faster. Temples, which have less circulation, respond poorly. Acne may produce sequels that are thickened or, more commonly, depressed (atrophic changes).
pathology of an acne scar
The following wound healing scenario may explain the pathology and formation of acne scars. Acne as well as any other cause for a minor wound may follow the same pathway. The initial step is defined by a structured series involving inflammatory cells. This
succession of episodes is arranged by neutrophils. Subsequently, macrophages elaborate
a variety of cytokines, which create an environment prone to granulation
tissue constitution. Eventually, migration of fibroblasts coincide with
proliferation and recapitulation by depositing new collagen. Simultaneously,
production of new capillaries is triggered by some factors released
in the wound section. A problem arises when this organized cascade
is disrupted by its anabolic and catabolic phases. An overreacting
wound healing response may happen, creating a bulgy lesion of fibrotic tissue. Alternatively, deleted connective tissue is deficiently replaced and forms a pitted appearance resembling
the surface of a golf ball. In either case, the scar often is a legacy of skewed
healing process. Pathology of spots and discolorations resulted from acne, however, have less correlation with anabolic
and catabolic stages, rather, skin pigmentation changes arise prominently.
Types and prognosis
Types of acne scars are the most important factor in determining its appropriate treatmnet. There are basically two types of scars. One is associated with propagated tissue generation and the other is associated with some tissue loss
Types with increased skin tissue:
Keloids: They present as smooth, firm, irregularly shaped lesions. Upper body
or angle of the jaw are more prone to these type of facial scarring.
Skin of dark-complexions (black skin) is more predisposed to develop
hypertrophic scars. They could be regarded as thick, raised, lobulated fibrotic plaques. Types with increased skin tissue rarely observed with acne even in prolonged severe cases.
Types with loss of skin tissue:
Acne spots: Flat discolorations either brown or red.They
are more likely to fade away either gradually without treatment or using fading creams. Post inflammatory pigmentations are classified in the same category. Blocks of pink hyperpigmentations
seen following skin breakouts and more likely prolonged acne.
Ice-pick lesions: They may be superficial or deep, fairly linear but irregular and
generally turn out on the cheeks. These lesions are variably resistant to
the treatments and the more penetrating they are the longer it takes
to be healed totally. Acne lesions can lead to ice pick scars.
Depressed fibrotic scars: They present as large with sharp margins and steep
sides. Their base is rigid, white and can not be stretched. They
may result from severe lesions such as cystic and nodular forms of acne. Read more on depressed scars and their management.
Atrophic scar macules:
This type of lesions manifest as soft, distensible, ivory-white
in color and small in size (few millimeter in diameter). Acne is
recurrently associated with atrophic scars.
Acne scars are result of improper deposition of collagen
and elastin and insufficient wound repair process. Lining epithelium is
not flat and atrophic but hyperplastic. Healing them involves inducement
of the skin's repair mechanisms and rebuilding elastin and other
fibers. Overall they have a good prognosis. They do not expand in size or number over time. However, aging has an adverse effect on acne caused scarring and render them more pronounced.
Prevention:
The more acne
inflammation persists the more likely development of scarring is. Treatment promptly in its course is the best method for prevention of acne
damages. Use of anti oxidants as a preventive method especially
vitamin E is still viewed with skepticism, some studies even report
a harmful effect. Powerful anti oxidants such as alpha lipoic acid
when employed alone works with no success. A
favorable medication for acne essentially address the following
problems: An elevated sebum synthesis, overproduction of epithelial
cells lining follicles, bacterial involvement, more inflammation
in acne sites. Read also next page for more
prevention tips. Another treatment that has been used by Mayo is application of butulinum toxin to help more effective of natural repair system by reducing muscle tension around the wound. It seems that muscle spasm has a detrimental effect on realinneation of collagen fibers even if we could for a moment ignore a decrease in blood circulation and inflammatory response secondary to muscle spasm. Read more on botulinum and its effect for a better healing of a wound and less scar generation.
acne scarring repair, different removal techniques for facial restoration
Most have heard of chemical
peels, dermabrasion, silicone injections, collagen
implants and laser treatment since these have been widely
publicized in the lay press for treating acne scarring. For the patient whose acne
has recently cleared, it is worthy to know that scars tends to
become less apparent with time and that any consideration of cosmetic
surgery must be deferred for some time. Post inflammatory pigmentations
tend to disappear in a few months. So post inflammatory pigmentations
in most cases resolves spontaneously. It ought to be pointed out
that lesions on the body does not tend to improve as readily and is
conventionally less amenable to cosmetic surgery. Read more:
Topical treatments (creams/serums/skin products), Oral treatments:
Retinoic acid, alpha and beta hydroxy peels, potent anti oxidants such as alpha lipoic acid creams are widely discussed and debated in treatment of acne sequels inculding acne hyperpigmentation spots, scars and lack of skin uniformity. Among medications for acne scars is retinoic acid cream. Despite showing some degree of improvement, its use alone does not bring about a dramatic conversion. Skin dryness and redness are among complications. Here is more information on creams for eliminatin of scarring resulted from acne. Oral medications such as accutane are not very pleasing to most affected individuals and does not alter lesions to a noticeable extent.
acne Scar excision (subcision): This surgical method of treatment uses a scalpel or punch to remove the damaged skin. Under local anesthesia, the lesion is excised and the skin edges are then sutured together. Excision is typically recommended to patients with deep pitted marks that are not amendable to the TCA technique. Good for deeper marks. Longer recovery time. Read more on this technique (excision-subcision) from medscape.
Iontophoresis:
New study suggests use of ionophoresis for atrophic scars usually resulted from acne with either tretinoin or estriol. In iontophoresis an ionizable drug is injected into the skin using an eletrical discharge without use of a needle.
Microdermabrasion:
Dermabrasion involves controlled surgical scraping that resurfaces the outermost layers of the skin
to give a smoother appearance. It can be done over the full surface
of the face or on small areas. Dermabrasion also may be done in
conjunction with other cosmetic procedures such as a chemical peeling
or face lift. Dermabrasion is used to treat a range of skin imperfections
including: Wrinkles and frown lines, pre-cancerous skin growths
(keratoses), face scarring (excluding burn scars, acne scars),
post-surgery marks, skin pigmentation, sun damage, tattoos,
age spots, facial freckles, acne discoloration spots and other forms.
Acupuncture:
Use of acupunture for acne scars repair is considered a new approach. Use of small, very thin needles in the skin causes a tiny injury at its site which is associated with an increase in skin microcirculation and stimulation of inflammatory mediators. Infiltration of cytokines is chemotactic for fibroblasts and production of new collagen. Acupuncture seems to be rather effective in improving appearance of atrophic acne scars. Facial acupuncture is becoming more popular not only for treatment of acne scars but for other rejuvenating purposes.
resurfacing by laser for acne scars
Another technique for acne
scar removal appear to be more with a desirable outcome in convex
regions of the face. Lateral cheek and the temples do not benefit
from this office procedure as much. Laser resurfacing treatments could be associated with hyperpigmentation (increased skin color)
or hypopigmentation (decreased skin color) for short or long term
in treatment vicinities. Scars, infection and persistent redness
are also possible side effects of laser resurfacing. With available medications these
could be controlled. Some clinical testing suggest that high-energy,
pulsed CO2 laser can safely and effectively improve or
even eliminate atrophic acne damages and provides many contributions
in contrast with traditional treatment means. Erbium, the latest
technique, has generated more satisfactory results which leads to
elimination of a superficial acne scarring and a reduction in other
forms of scars. One study suggests more effective result with laser punch-out method. Some research indicate that old severe scarring responds substantially less to laser treatments while newly formed
marks could almost completely vanish. This indicates that timing
of treatment could be significant. Laser also have been utilized
to treat acne particularly in patients who show sensitivity reactions
to medications for acne. Outcomes are not very promising though and cost is another consideration.
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